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Daily intake and long-term consistency matter most

With poorly controlled or severe disease, there is risk that extra-articular manifestations such as keratitis, pulmonary granulomas (rheumatoid nodules), pericarditis/pleuritis, small vessel vasculitis, and other non-specific extra-articular symptoms will develop

Future considerations should include making use of a qualitative approach meta-analysis to strengthen the presented evidence

Considering its used off-label (that is, for reasons other than acne) to prevent aging, this is literally the opposite of what youd expect or hope to happen

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