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Am J Kidney Dis 2012;60:850886 Intensive diabetes management with the goal of achieving near-normoglycemia has been shown in large prospective randomized studies to delay the onset and progression of increased urinary albumin excretion and reduced eGFR in patients with type 1 diabetes (1) and type 2 diabetes (34)
Rosenstock, J., Fras, J
Someone starting at 300 pounds with significant insulin resistance may lose 12 pounds in the first month
Importantly, the association persisted after propensity matching and multivariable adjustment, and remained robust across multiple parameterizations of disease severity using the At the same time, effects were concentrated among patients with BMI 35 in several different types of statistical modeling, indicating that the benefit may be driven by attenuation of the adverse physiology associated with excess adiposity, he added
Ullmann JFP, Janke AL, Reutens D, Watson C
