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Large and complex studies are needed to identify and detail the changes at the mitochondrial level and the therapeutic approaches ( Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated pleiotropic effects, including reducing mitochondrial ROS generation

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Going forward, theres better peptide stability and specificity, combinations with stem cells or gene editing, and personalized regimens, so follow new clinical trials and regulatory guidance when designing treatment

Posted July 7, 2025 Reviewed by Monica Vilhauer Ph.D

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