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Restarting typically begins at your previous effective dose rather than starting fresh, since your body retains some physiological adaptation from prior treatment

Here is what is happening inside the body: Digestion slows slightly so meals keep you full longer Blood sugar becomes more stable, which reduces energy crashes Hunger and cravings become quieter and easier to understand Fullness signals activate earlier during meals Women often describe the first noticeable difference as a mental shift

Nauck MA, Muus Ghorbani ML, Kreiner E, Saevereid HA, Buse JB, LEADER Publication Committee on behalf of the LEADER Trial Investigators

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So taking the two together can increase the risk of hypoglycemia