Both reduce hangover severity by 4050% when dosed preventively, but NAC costs one-tenth as much ($0.30 per dose vs $23 for liposomal glutathione) and has a 3060 minute slower onset due to the conversion step
Its part of why the formula feels high-end when you apply it

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When the body is in a state of hypoxia, infection, intense exercise, etc, and the cells demand for ATP increases, pyruvate and NADH tends to be directly catalyzed by lactate dehydrogenase (LDH) to produce lactate, rather than entering the mitochondria to participate in the tricarboxylic acid cycle (TCA)
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A typical treatment plan involves 3 to 5 sessions for optimal results, making it a relatively affordable option compared to lasers