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The copper chelator tetrathiomolybdate, which blocks the copper-dependent catalytic activity of LOX, is presently undergoing a phase II study (NCT00195091) involving patients with breast cancer at moderate to high risk of recurrence

While ATCUN motifs efficiently complex with Cu(II), they are unable to effectively reduce Cu(II) as they do not bind well to Cu(I) and thus less readily act as redox intermediates 10

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Since the majority of the body's glutathione is stored inside cells, a whole-blood test is generally considered more reliable than testing just the plasma (the liquid portion of the blood)

Che Y, Shi Y, Xu Y, Guo S, Liu H, Yang J, Liu J, Niu J, Shi W, Guo L, et al