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Kidney and cardiovascular outcomes SURPASS-4 kidney composite HR 0.58, slower eGFR decline (-1.4 vs -3.6 mL/min/1.73m2/yr), UACR -6.8% vs +36.9%
Chew food thoroughly to aid digestion, eat slowly to reduce air swallowing (which can contribute to burping), and avoid carbonated beverages, which introduce additional gas into the digestive system
If semaglutide at $199/month produces 15% weight loss and tirzepatide at $349/month produces 22.5% weight loss, the cost per percentage point of weight loss is roughly equal
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Before starting tirzepatide Baseline labs: Total testosterone, free testosterone, estradiol, SHBG, LH, FSH, complete metabolic panel, lipid panel, HbA1c, vitamin D, zinc, B12