In short, isotretinoin is a medication used to treat severe cases of acne, in most cases cystic or stubborn acne that has not responded to other well-known acne treatments
But in the meantime, it could help users with more than just compulsive eating
And for some people, constipation is one of the most persistent
It is licensed in the UK for adults with obesity (BMI of 30 or above), or overweight adults (BMI of 27 or above) who also have a weight-related health condition
Diabetes Obes Metab 22(12):24872492 Verma S, Bhatta M, Davies M, Deanfield JE, Garvey WT, Jensen C, et al (2023) Effects of once-weekly semaglutide 2.4 mg on C-reactive protein in adults with overweight or obesity (STEP 1, 2, and 3): Exploratory analyses of three randomised, double-blind, placebo-controlled, phase 3 trials
Applying a clinically meaningful number or difference helps to prevent trials from being declared positive based solely on statistical significance