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The one-tailed Student t -test was only used to analyze the effect of AEF0117 on reality testing and the effect of rimonabant on sucrose intake and behavior in the EPM

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SURMOUNT-4 results are available on PubMed

In addition to the reduction in body weight, improvement in liver injury rates and resolution of steatohepatitis in 39% of cases, treatment with liraglutide was associated with lower progression of liver fibrosis compared to placebo

Conversely, Nrf2 activationby pharmacological agents or genetic meansupregulates GSH, GPX4, and FTH1, mitigating podocyte injury and DN progression (120, 148, 149)