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18 When coupled with smaller and more infrequent meals, bile salt secretion into the intestine is decreased, reducing gallbladder motility and triggering the formation of biliary sludge, i.e., crystals or microliths composed of precipitated lipid particles

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Ungar, PhD, a professor at Penn Engineering, notes that while clinical trials are excellent at flagging high-risk safety concerns, they often overlook the day-to-day symptoms that bother patients the most

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Patients receiving tirzepatide 15 mg lost an average of 12.4 kg (about 13.1% of baseline weight), roughly double the 6.2 kg (6.7%) seen with semaglutide