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When the breakdown of fatty acids is impaired, they accumulate in the nerve sheath (called myelin)

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A diet rich in animal products, fortified foods, nutritional yeast, and supplements helps maintain adequate B12 levels

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12 , 13 Moderate physical activity and healthy diets promote a balanced microbiome (eg, a high Bacteroidetes to Firmicutes ratio) along with the production of neurotransmitters (eg, serotonin, dopamine), secondary bile acids, and short-chain fatty acids, including acetate, propionate, and butyrate (Figure 1)