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Historically, BB was discovered because of its role as the proximate endogenous biosynthetic intermediate in l-carnitine synthesis in mammals, a multistep pathway that generates l-carnitine from lysine (3234)

[DOI] [PMC free article] [PubMed] [Google Scholar] Orr ST, Ripp SL, Ballard TE, Henderson JL, Scott DO, Obach RS, Sun H, and Kalgutkar AS (2012) Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks

The achieved allicin solution was dried with freeze drier and the resulting allicin powder was used for all experiments

Spots not stored under these conditions gradually loose the enzyme activity due to heat inactivation, causing potential risk of misclassifying samples as screen-positive (34,35)

Key Advantages Over Other Methods: Faster uptake than oral supplements (no gut breakdown)

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