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The animals were fed standard chow for 1 week in a suitable experimental environment with a 12-h/12-h light/dark cycle and a controlled temperature (25C 1C) and humidity (50 10%)
This coping mechanism can increase carb intake , which may slow or block weight loss
Key mechanisms include: Stimulation of collagen and elastin synthesis in fibroblasts Activation of lysyl oxidase for collagen cross-linking Enhanced production of glycosaminoglycans and decorin Modulation of metalloproteinase activity for controlled matrix breakdown The copper ion serves as an essential cofactor for enzymes involved in collagen synthesis and provides antioxidant protection through superoxide dismutase activation
