These lessons create a foundation for long-term health that extends beyond the number on the scale
Gerstein HC, Sattar N, Rosenstock J, Ramasundarahettige C, Pratley R, Lopes RD, Lam CSP, Khurmi NS, Heenan L, Del Prato S, Dyal L, Branch K
Roberto Anichini (Diabetes Unit, Area Pistoiese USL Toscana Centro)
J.BriocheT.Gomez-CabreraM
First, Why Are People Switching
Abbreviations CNS: Central nervous system CVOT: Cardiovascular outcome trial GIP: Glucose-dependent insulinotropic polypeptide GIPR: Glucose-dependent insulinotropic polypeptide receptor GLP-1: Glucagon-like peptide-1 GLP-1R: Glucagon-like peptide-1 receptor GLP-1RA: Glucagon-like peptide-1 receptor agonist GPR: G-protein-coupled receptor HFpEF: Heart failure and preserved ejection fraction IEL: Intraepithelial lymphocyte LPS: Lipopolysaccharide MACE: Major adverse cardiovascular events MPGF: Major proglucagon fragment MTC: Medullary thyroid cancer NASH: Non-alcoholic steatohepatitis SGLT: Sodiumglucose cotransporter WAT: White adipose tissue References Bayliss WM, Starling EH (1902) The mechanism of pancreatic secretion
