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Subsequently, host ribosomes are hijacked to produce the two viral replicase polyproteins, which can further be processed into 16 mature NSPs through two virus-encoding proteases: main protease (M pro ) and papain-like protease (PL pro )

National Academies of Sciences, 2000)

Then, 20 L of MTT solutions was added to each well followed by an incubation period of 3 hours, then the media were removed and 200 l of DMSO was added to dissolve the crystal and the absorbance was recorded at 570 nm (BioTek, USA) and cell viability was calculated as a percentage compared to cells treated with DMEM alone

Rho-kinase inhibitors as a novel medication for glaucoma treatment a review of the literature

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