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Retatrutide is not yet FDA-approved , and thus remains officially an investigational therapy

Some patients notice improvements in morning stiffness and pain levels as early as weeks 3 to 4

Epidemiological analyses further suggest reduced incidence of dementia, Parkinson disease, and multiple sclerosis among long-term GLP-1RA users

The rate of discontinuation due to adverse events varied from 5% to 19%, predominantly due to gastrointestinal side effects [17]

Clinical profile and treatment patterns in individuals with type 2 diabetes and chronic kidney disease who initiate a GLP-1 receptor agonist: a multinational cohort study

Nasiri AmiriFRamezani TehraniFSimbarMMontazeriAMohammadpour ThamtanR