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Higher dosing: Some protocols use 500-750mcg twice daily for more severe injuries or faster results

It mimics endogenous GLP-1, enhancing glucose-dependent insulin secretion, decreasing glucagon secretion, and significantly reducing appetite and energy intake, which leads to clinically meaningful weight loss

Weight reduction: Clinical trials report substantial bodyweight loss (up to ~11 kg more than GLP1 RA comparators over 26 weeks at higher doses) [3] [4]

Completing the full 4 to 8 week protocol allows tissue remodeling to progress toward mature, strong collagen architecture

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