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Although studies have suggested a role for superoxide dismutase (23), the relationships with redox changes and clinical parameters have generally been weak, supporting involvement of other pathways

Our results clearly demonstrated that HFD consumption was associated with hepatic activation of both JNK and caspase-3 (Fig

SODs are classified into three isozymes based on the metal ion it binds, Mn-SOD (localized in mitochondria), Fe-SOD (localized in chloroplasts), and Cu/Zn-SOD (localized in cytosol, peroxisomes, and chloroplasts) (Mittler, 2002)

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An interaction with glutathione/glutaredoxin has been observed in all roGFP-based sensors generated to date 19,35,49,50,51,52,53 and it is unclear why this interaction should not also occur in the context of the NERNST probe