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The amino acid sequences of GLP-1 and its analoguesExenatide, Liraglutide, Lixisenatide, Semaglutide, Dulaglutide, and Albiglutideare shown

In contrast, Mounjaros active ingredient, tirzepatide, targets GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

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Wegovy injections ~15% over 68 weeks

Hum Mol Genet 21(17):37763784