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Glucocorticoids suppress glp-1 secretion: possible contribution to their diabetogenic effects

Another consideration that many people miss is light exposure

Why you cannot simply convert doses between peptides A question that comes up constantly: "I am on 10mg of tirzepatide, what is the equivalent retatrutide dose?" The honest answer is that there is no direct equivalence

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This collection brings together everything I have written about GLP-1 medications on this Substack, from the science of how they work to the practical questions you should be asking before you start one