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reported that CPF induces cell death and apoptosis in testicular cells, including GC-1 spg, TM3, and TM4 cells via oxidative stress in via increased p-AMPK levels [49]

Under physiological conditions, chaperone-mediated autophagy (CMA) degrades soluble -syn via heat shock cognate protein 70 (HSC70) recognition of KFERQ motifs and LAMP2A-mediated lysosomal transport [165]

Several types of cancer cells have been reported to have altered metabolism, such as high levels of iron uptake and ROS which make the cells sensitive to ferroptosis [251]

There is also a growing body of literature implicating disturbances in oxidation/reduction (redox) reactions and impaired antioxidant defenses as a risk factor for asthma development and asthma severity

Free Radical Biology, 45 , 559567

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