Luminescence measurement was performed by multi-mode microplate reader (FLUOstar Omega)
Safety and Side Effects Tirzepatide is effective but not risk-free
Shibuya T, Fushimi N, Kawai M, Yoshida Y, Hachiya H, Ito S, et al
Regulatory Peptides 161.1-3 (2010): 58-66
For example, copper ions can lead to GSH depletion through two mechanisms: the direct downregulation via the redox reaction between Cu 2+ and intracellular GSH, and the activation of a Fenton-like reaction by generating Cu + to amplify oxidative stress ( in situ GSH in tumor triggered mCMSNs biodegradation and reduced Cu 2+ into Cu + for enhanced hydroxyl radical production, leading to a powerful inhibition effect on tumors (Liu et al., 2019)
Additionally, oxidative stress markers, such as malondialdehyde (MDA), glutathione peroxidase (GPx), and superoxide dismutase (SOD) levels, were quantified to examine glycitins impact on oxidative stress