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Selectivity validation using GSH-depleted controls (e.g., buthionine sulfoximine [BSO]-treated cells) is a standard practice in well-designed preclinical studies
This powerful antioxidant works by interfering with the melanin synthesis pathway at multiple points, effectively reducing the production of excess pigment that contributes to skin discoloration
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The physician reviews medical history, current medications, allergies, kidney function and any cardiac history
7 Mitigating lipid peroxidation without compromising therapy using nanotechnology This section explores three critical areas of nanotechnology-driven approaches: combination of antioxidants and anticancer drugs, drug-loaded antioxidant nanoparticles, and drug carriers responding to stimuli for targeted release in cancer management
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