Providers may, in their clinical discretion, prescribe it off-label if deemed appropriate for their patient
So far, injectable obesity medications have proven to be highly efficacious and safe for use, but persistence on therapy remains challenging, Dr Aronne said
Severe Gastrointestinal Adverse Reactions Inform patients of the potential risk of severe gastrointestinal adverse reactions
Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5% of body weight
For the observed change over time in hunger, fullness, and difficulty resisting cravings, positive responses with semaglutide were observed early and then reached an equilibrium with placebo at the end of the study
Smaller, more frequent meals are generally better tolerated than large ones because GLP-1 medications slow gastric emptying