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The most defensible synthesis is that the effect of a free synthetic MGF peptide on cultured myoblasts is weak or absent, while E-domain sequences expressed endogenously in vivo do produce measurable, though context- and age-limited, effects two statements that are only superficially contradictory once the difference in experimental design is appreciated
The cost of these drugs will clearly and profoundly exacerbate inequities, since they are eminently affordable by the rich, but the need is extreme among the indigent
Smith JF, Shindel AW, Huang YC, et al