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80 While the clinical significance of this heart rate increase remains uncertain, it raises theoretical concerns in patients with ischemic heart disease or arrhythmias and may counteract some of the antihypertensive benefit of GLP-1 RAs

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The result is systemic rather than localized

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A 2024 study found that GLP-1 drugs can likely be manufactured more cheaply than their current market costs of, for example, $95 in Brazil, $115 in South Africa, and $353 in the United States

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How GLP-1 Drugs Help Quiet Obsessive Thoughts About Food, accessed April 22, 2025, What is food noise

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But like many trending health topics, the conversation has gotten messy

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Behavioral effects of clozapine: involvement of trace amine pathways in C

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