Complementary clinical and meta-analytic data consistently demonstrate systemic redox imbalance, including lower glutathione reserves, altered GSH/GSSG ratios, increased lipid peroxidation, and dysregulated NRF2 signaling, linking oxidative status to immune activation and synaptic dysfunction (James et al., 2004
Inborn errors of metabolism with myopathy: defects of fatty acid oxidation and the carnitine shuttle system
TMAOs effects extend to systemic arterial hypertension and vascular disorders, where elevated levels are associated with unfavorable cardiovascular events
Effect of one-year vitamin C- and E-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease
Revista Mackenzie de Educao Fsica e Esporte 2009, 8 (1): 135-145 4
Keshani M, Alikiaii B, Askari G, Yahyapoor F, Ferns GA, Bagherniya M (2022) The effects of L-carnitine supplementation on inflammatory factors, oxidative stress, and clinical outcomes in patients with sepsis admitted to the intensive care unit (ICU): study protocol for a double blind, randomized, placebo-controlled clinical trial