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The potential of developing durian pulp extract as a functional dietary supplement for preventing and protecting against neurodegeneration is promising

Meanwhile, research has shown that A may also induce the generation of reactive oxygen species (ROS) through various pathways, causing lipid peroxidation and neuronal oxidative stress, which causes further neuroinflammatory injury [17,18,19]

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Specifically, the HFD group exhibited significant induction of genes encoding various collagen subtypes (most notably Col1a1 , 8.5-fold), other critical ECM glycoproteins and adhesion molecules (e.g., Spp1 , 13.7-fold