378 On the basis of the increased activity of -gal in senescent cells, a new prodrug, SSK1, which can be specifically cleaved by lysosomal -gal into cytotoxic substances and induce the apoptosis of senescent cells, thereby eliminating senescent cells, was developed
Son K, et al
Carnitine acquisition and transport: mechanisms and regulation of metabolic homeostasis Carnitine homeostasis, essential for mediating mitochondrial fatty acid transport and -oxidation, is maintained through a delicate balance between exogenous acquisition and endogenous synthesis, alongside precise transport mechanisms under physiological conditions [56, 57]
It also activates the Keap1/Nrf2/HO-1 signaling pathway, enhancing antioxidant defenses and reducing oxidative stress markers such as ROS [105]
Palatini, P
GHRH stands for Growth Hormone Releasing Hormone, which admittedly seems like a mouthful of double talk, and in a way, it is