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doi: 10.1161/CIRCULATIONAHA.110.956839 124 HaradaR.HayakawaY.EzuraM.LerdsirisukP.DuY.IshikawaY.et al

Lifestyle interventions may sustain weight maintenance and metabolic health after GLP1 RA discontinuation

Escalating demand: Since 2023, prescriptions for GLP-1 medications have increased dramatically nationwide as they gained popularity for weight loss

Intramuscular injection near an injury site (a common self-administration approach) adds a theoretical local concentration benefit that has some support in animal wound models but has not been tested head-to-head against subcutaneous delivery in a controlled trial

It can also inhibit cyclooxygenase-2 (COX2) activity by reducing NO production, thereby reducing prostaglandin E2 (PGE2, an important pro-inflammatory mediator)

Stay consistent: Take your supplement at the same time each day and give your body at least two months to show results