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Researchers, clinicians, and people who've already cycled through the first two generations of GLP-1 drugs want to know: is this the next level, and when can you actually get it

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The Aon analytics team expanded our real-world data analysis to nearly 200K GLP-1 patients with 6 months of new 2025 experience

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In this systematic review and meta-analysis of 25 randomised controlled trials involving more than 8,000 participants, we found that people allocated to GLP-1 receptor agonists reported lower binge eating symptoms, loss of control eating, eating disinhibition, and emotional eating compared with those allocated to control groups

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[25] [26] NICE recommends GLP-1 receptor agonists as second- or third-line therapy for type 2 diabetes when metformin and other oral agents have not achieved adequate control

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For a subset of plastic surgeons, the GLP-1/aesthetics crossover moment also included prescribing semaglutide (the active ingredient in Ozempic and Wegovy) to select patients before body-contouring procedures, like tummy tucks, to help them reach a safe weight for surgery (higher BMIs are associated with a greater risk of complications) and to shrink the visceral fat in their abdomens, allowing for a more dramatic cinching of waistlines

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