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Key points Glucagon-like peptide 1 receptor (GLP1R) agonists and dipeptidyl peptidase 4 (DPP4) inhibitors reduce the onset and progression of albuminuria in patients with type 2 diabetes mellitus (T2DM)

This result suggests that the SNS was activated during maximal ACEI and sitagliptin treatment (86)

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By targeting the AMPK pathway, it optimizes the bodys fat-burning potential, making it more manageable to achieve weight loss objectives

If results are consistent with phase 2 data, an FDA submission could follow, with potential approval expected in 2026 or 2027