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Tirzepatide generally shows favorable safety signals including lower GI event rates, better muscle preservation, and protective kidney effects

Finally, we identified six papers describing favorable associations between GLP-related molecules (that is, geniposide, GLP2, puerarin) and reductions in depression-like behavior 170,171,172,173,174,175

Lepage L, Dufour A-C, Doiron J, Handfield K, Desforges K, Bell R, et al

Although more research is needed to understand if GLP-1 drugs affect bone health, experts have expressed concern that people taking the appetite-suppressing shots and pills dont get enough nutrients, including the bone-building vitamin D

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doi: 10.1016/j.gtc.2023.02.003