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In a trial of patients with T2DM and BMI 27 kg/m2 or more receiving semaglutide injection for weight management, retinal disorders were reported by 6.9% of patients treated with semaglutide 2.4 mg/week, 6.2% of patients treated with semaglutide 1 mg/week, and 4.2% of patients treated with placebo

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Tan A induced ferroptosis by P53-mediated SLC7A11 downregulation to inhibit the proliferation of gastric cancer (Guan et al., 2020)