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Recently, a phase 2b study for people with obesity has been completed and a press release revealed that danuglipron doses between 40 and 200 mg twice daily led up to 11.7% WL compared to 1.4% weight gain with placebo after 32 weeks of treatment [27]

Some gastrointestinal adverse events like viral gastroenteritis, feces hardness, and infrequent bowel movements were reported in a limited number of trials, restricting the ability to perform robust statistical analyses and draw definitive conclusions for those specific outcomes