222 Although limited direct evidence has evaluated use of GLP-1s with or without RDN-provided MNT, the SCALE, 13 STEP 1, 14 SURMOUNT, 15 and STEP 3 178 trials each demonstrated substantial weight reduction by combining GLP-1s with regular counseling sessions by RDNs or other qualified healthcare professionals (such lifestyle support was also provided to the placebo group in each trial)
Now let's systematically address potential issues

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People call it an antimicrobial peptide, but that label is only part of the story
No human trials have been conducted for osteoporosis
I personally have two copies of the MTHFR mutation and am alive and well (with some interventions), while others I have seen have just one copy of a mutated gene, and a lot of symptoms