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They increase dopamine, acetylcholine, serotonin, or GABA to produce short-term improvements in focus, mood, or alertness

Nine (64%) were 5-year exclusivities awarded for approval of new chemical entities, while the other 5 (36%) were 3-year exclusivities awarded for approval of new investigations or combinations

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Homodimers It is a general physical property of the class-A GPCRs to form transient homodimerization (47), which can be confirmed by the minimal single functional unit consist of D2R homodimers and a G protein, mediated by direct association among receptors (48)