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Discussion Overall, no consistent or clinically relevant pattern of increase or decrease in semaglutide exposure (AUC from time zero to 24 h [AUC 24 ] and maximum concentration [ C max ]) between subjects with varying degrees of renal impairment and normal renal function was observed after 10 consecutive days of once-daily oral administration
So, a denial often changes the financial strategy more than the clinical conversation
Therefore, fibre, which tends to reduce insulin, should not be counted and think that the net carbs (carbs minus fibre) concept makes good sense
10.7417/T.2017.2002 29 ChoiS
Lets make sure we look at whats proven and safe first. Weight loss discussions are common, given that GLP1 receptor agonists often lead to reduced appetite and weight change