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Other Ingredients: Purified (deionized) water, natural flavors (orange-pineapple, lemon-lime), glycerin, potassium sorbate

In particular, proving bioequivalence on these products may be easier given their systemic mechanism of action (in contrast to inhalers, which act locally) and the ability for generic firms to apply simpler in vivo techniques when seeking FDA approval

As above, full details and formulas appear in Addition File 1

On the other hand, taste-related complaints frequently co-occur with gastrointestinal symptoms such as nausea and early satiety (35, 68), making it difficult to distinguish between objective gustatory dysfunction (sensory) and reward revaluation driven by state-related signals (liking/wanting) at the clinical level

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A 2-year randomized controlled trial with low-dose B-vitamin supplementation shows benefits on bone mineral density in adults with lower B12 status