Hepatology 67 , 12611269 (2018)
However, tumors evolve multiple mechanisms to re-educate immune cells into pro-tumor phenotypes, such as secreting high levels of immunosuppressive cytokines (e.g., IL-10, TGF-) 4 or creating a hypoxic environment 5
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While research is still developing, this approach reflects a meaningful shift toward treating the root inflammation rather than just managing pain in the moment