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Di Marco et al., 2022)

Clinical trial data suggest that gastrointestinal side effects, including any reflux symptoms, typically improve over time as patients develop tolerance to the medication

In clinical trials, gastrointestinal adverse events were the most frequent reason for treatment discontinuation, though most cases were mild to moderate in severity and transient in nature

These are not dramatic results, yet they can be meaningful when combined with a thoughtful, sustainable program

Aligning larger meals with periods of peak insulin sensitivity may enhance Retatrutides effects

If you already drink coffee, there is likely no need to stop