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226 Although most uptake of cellular iron is mediated by TFR1, iron can be directly taken up by DMT1, which is required for cells to package insulin during secretory granule formation

The endpoint outcome, rather than any safety signal, is what redirected the program

experimental studies

Repeated IV use has been linked in some reports to thyroid disruption, kidney stress at high doses, and occasional skin reactions

Estimates of all-cause mortality, cause-specific mortality, and 95% CI are based on the Poisson distribution, where mortality is expressed as the number of deaths per 1000 person-years of follow-up

Composition and procedure for disinfecting blood and blood components