Dabigatran is a P-gp substrate but is not metabolized by CYP3A4, so the pharmacokinetic concern would be limited to P-gp
Biol Reprod 62:390397 Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA et al (2016) NAD(+) replenishment improves lifespan and healthspan in ataxia telangiectasia models via mitophagy and DNA repair
Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-B1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients
Although statistically significant, these effects remain smaller than those achieved with retinoids or growth factor formulations
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