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doi: 10.1111/j.1523-5378.2009.00686.x 44 DingSZMinoharaYFanXJWangJReyesVEPatelJet al

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The C5a/C5aR1 axis drives TAM immunosuppression in solid tumors, with oral inhibitor PMX53 showing preclinical efficacy [77]

Adherence is significantly lower among those using GLP-1s for weight loss versus those using them to manage type 2 diabetes one study found that about 65% of patients without type 2 diabetes discontinued GLP-1 therapy within one year, compared to 47% of patients with type 2 diabetes

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