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231 In an NAFLD mouse model, FMT from mice treated with Qushi Huayu decoction confirmed that its induced gut flora remodeling partially mediated the efficacy

The peptides reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression, and improved blood flow all contribute to nerve recovery potential

Nevertheless, SASP can increase mortality in mice and also cause adverse effects such as weight loss and hypothermia, regardless of the impact of intact SASP or its metabolites on the system (89)

Increasing glutathione levels may help improve symptoms and reduce the incidence of bacterial infections [38, 39, 40]

However, in those cells incubated with DEM that were in culture for 6 days glutathionylation of nuclear proteins increased to values even higher than controls or BSO treated cells

135 Dihydroartemisinin can significantly inhibit the viability of leukemia cells, causing cell cycle G0/G1 phase arrest and ferroptosis, and the mechanism may be related to inducing autophagy and accelerating ferritin degradation by regulating AMP-activated kinase (AMPK)/mTOR/p70S6k signaling pathway