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The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

19,20 This explains why any weight loss immediately triggers compensatory neurohormonal pathways (e.g

Verweij, Ruud T.M

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Brain lipid peroxidation and alzheimer disease: synergy between the Butterfield and Mattson laboratories