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Encouragingly, in the retatrutide 12 mg escalation group, individuals showed up to ~17% bodyweight reductions at 36 weeks, a magnitude of reduction not documented till date in any other phase II\ III trials testing GLP-1 and GLP-1 receptor agonists in people with T2D
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However, the effect varies between individuals, and fertility is affected by many different factors in addition to body weight and metabolic health
The short answer is yes, many patients take both medications simultaneously
It is unknown whether our patients were taking supplements specifically to manage ME/CFS symptoms and whether they initiated use on their own or on the advice of a clinician
The weight loss effects of semaglutide stems from its chemical structure
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