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Vitamin B12 injections are primarily used to: Treat or prevent vitamin B12 deficiency Manage pernicious anemia Support patients with malabsorption disorders Aid those with dietary restrictions, such as vegans or vegetarians Offset vitamin loss due to medications like metformin or proton pump inhibitors (PPIs)

10.1016/j.jmbbm.2013.08.004 31 ChungH

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This connection has led researchers to focus on better understanding the effect of low vitamin B12 on obesity, insulin resistance, type 2 diabetes, and cardiovascular disease

The performance improvement could partially stem from modified behavioral states

It reduces methylationdriven consumption of NAM, increases substrate availability for NAD+ synthesis, and promotes NAD+ biosynthesis to elevate intracellular NAD+ levels