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That is the single most useful framing for this question, so the rest of the guide is organized around it

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According to the classic two-hits model, the increased insulin resistance, secondary to metabolic syndrome, determines an excessive lipid accumulation in healthy hepatocytes (first hit), mainly through an increased mobilization of free fatty acids from visceral adipose tissue to the liver

Providers often request baseline blood work and repeat tests every 8 to 12 weeks in addition to monitoring changes in pain levels, mobility, and day-to-day function

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Do not blow on it or wave it dry