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Statements Author contributions SS: Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing original draft, Writing review & editing

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Then insert the needle into the vial with the sterile solvent

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However, under conditions of stress and inhibition of the electron transport chain, the enzyme works in the opposite direction by transferring electrons from NADPH to NAD + , which impairs mitochondrial antioxidant defenses and feeds more reducing equivalents into the impaired electron transport chain leading to increased electron leakage and superoxide formation [133]

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